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You won't be able to perform a mailbox level backup with NTBackup, which is the backup application included with Windows 2000. It can back up all databases, a single storage group or a single database; it cannot backup selective mailboxes.
So, if you are trying to back up at the mailbox level with NTBackup and can't, it's not a permissions problem. If you are using NTBackup and trying to back up a database or storage group and you are getting Access Denied, then this would indicate a permissions problem. Make sure the account under which you are running NTBackup has the appropriate permissions: Backup Operator or greater for Windows and Exchange Full Administrator for Exchange 2000.
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