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What you need to look at is a dedicated spam software solution. Antivirus vendors like Symantec have improved their products to included spam-filtering capabilities. But antispam vendors have the best products. I used iHateSpam from Sunbelt Software when I was running Exchange 2000 and I really liked it. You might also want to check out a managed service like Postini, which has been getting a lot of attention lately.
I'm not discouraging you from using blocklists, but I wouldn't depend on them. It is fairly easy for spammers to work around them by spoofing domains and IP addresses. A good site I would recommend looking at is SPAMHAUS.
MEMBER FEEDBACK TO THIS ASK THE EXPERT Q&A:
Richard is mistaken (out of date) about Symantec's antispam solution. It is called Symantec Premium Antispam, and is derived from their BrightMail acquisition last year. It works in conjunction with Symantec Mail Security, which the question-asker already has.
—David W.
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Brightmail, even though it is now owned by Symantec and aside from any bias, is still an add-on service that is subscription based and is not included with Symantec Antivirus for Exchange. Please see Symantec Mail Security for Microsoft Exchange.
—Richard Luckett, spam and security expert
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Related information from SearchExchange.com:
Learning Center: The spamfighter's toolbox
Reference Center: Spam prevention and management
Learning Guide: Malware
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