One important thing to note is if you plan on having Outlook 2003 clients in this environment, you'll need to install...
the Exchange 5.5 CDP Patch 2657.55 from here. Have a read through Microsoft Knowledge Base Article 301036 (HOW TO: Install and Configure Exchange Server 5.5 and the Active Directory Connector in a Windows 2000 Domain)prior to your installation to make sure you have the correct security settings configured in your environment.
Dig Deeper on Legacy Microsoft Exchange Servers
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